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BPS Pharmacotherapy (Part1 and Part2) Sample Questions:

1. A 70-year-old man has completed a 14-day course of sulfamethoxazole/trimethoprim for Escherichia coli cystourethritis. The patient has a Foley catheter. A urine culture obtained 24 hours after the last antibiotic dose shows Candida albicans > 10x3 cfu/mL, RBC > 100 cells/hpf, and WBC = 10-20 cells/hpf. The patient is asymptomatic. What is the most appropriate management?

A) Posaconazole orally daily for 5-10 days
B) No anti-infective needed
C) Fluconazole orally daily for 5-10 days
D) Amphotericin bladder irrigation for 5-10 days

2. A patient is started on ledipasvir-sofosbuvir. What would be the best indicator of treatment response?

A) HCV RNA below the lower limit of quantification
B) Absence of alpha-fetoprotein
C) Absence of cryoglobulinemia
D) ALT less than three times the upper limit of normal

3. A 42-year-old woman is diagnosed with deep vein thrombosis. Heparin therapy is initiated with
5,000 units as a single bolus injection, followed by an initial infusion rate of 1,000 units/h. The aPTT measured 6 hours later is >150 sec. Which of the following would be the most appropriate action at this time?

A) Stop the infusion until the aPTT falls to <50 sec, and then resume at 750 units/h.
B) Administer protamine 5 mg, and decrease the infusion rate to 750 units/h.
C) Stop the infusion for one hour, then resume at 750 units/h.
D) Continue the infusion at 1,000 units/h, since the aPTT was drawn too early and is not useful.

4. A 14-year-old boy has mild papulopustular acne on the forehead, the nose, and the cheeks, with sparse involvement of the upper trunk and the neck. Which of the following is the most appropriate initial therapeutic agent?

A) Topical isotretinoin
B) Topical erythromycin
C) Oral tretinoin
D) Topical benzoyl peroxide

5. Post myocardial infarction, a patient's cardiac profile and serum chemistry results show the following values:
Heart rate: 120 bpm
Blood pressure: 80/40 mm Hg
Pulmonary capillary Wedge pressure: 6 mm Hg
Right atrial pressure: 2 mm Hg
Cardiac index: 2.3 L/min/m2
Sodium: 136 mEq/L
Potassium: 4.2 mEq/L
Chloride: 98 mEq/L
Bicarbonate: 22 mEq/L
Blood urea nitrogen: 25 mg/dL
Creatinine: 1.0 mg/dL
Glucose: 110 mg/dL
Which one of the following therapeutic regimens is most appropriate for the initial treatment of this patient?

A) Furosemide 40 mg intravenous push
B) Nitroprusside 2 mcg/kg/min
C) Dopamine 15 mcg/kg/min
D) Normal saline 500 mL/h

Solutions: